Shim-pack GISS Series - Features
HPLC Column Solutions
Column Chemistries
Shim-pack GISS C18 | |
Bonded Phase | Octadecyl Groups |
Analysis Mode | Reversed Phase |
Features | High-speed analysis with ultra-high inertness and high durability |
Particle Size (μm) | 1.9, 3, 5 |
Pore Size (nm) | 20 |
Surface Area (m2/g)
|
200 |
Carbon Loading (%) | 9 |
End Cap | ○ |
pH Range | 1-10 |
USP Code | L1 |
High-speed analysis with ultra-high inertness and high durability
Analysis Examples
■Peaks (100 μg/L each)
Q1 > Q3 | |
1. Acebutolol | 337.10 > 116.05 (+) |
2. Atenolol | 267.25 > 145.00 (+) |
3. Labetalol | 329.00 > 161.95 (+) |
4. Nadolol | 310.05 > 254.00 (+) |
5. Pindolol | 249.80 > 116.00 (+) |
■Conditions
Column | Shim-pack GISS C18 (50 mmL x 2.1 mmI.D., 1.9 μm) |
Eluent | A) 10 mM Ammonium Formate in H2O B) 10 mM Ammonium Formate in CH3OH A/B = 70/30 ‒ 0.3min - 40/60 ‒ 0.5min - 0/100 ‒ 0.1min ‒ 0/100 ‒ 0.01min -70/30 ‒ 0.5min - 70/30, v/v |
Flow Rate | 0.6 mL/min |
Col. Temp. | 40 °C |
Detection | LC/MS/MS(ESI, Positive, Negative MRM) |