LCMS-8060 - Options

IonFocus unit

A newly-developed ESI probe with focus electrodes introduces ions into the mass spectrometer more effciently, while expelling contaminants to reduce noise and provide more stable data. In addition, an improved heat-assist design promotes the ionization of a wide range of compounds. (Patented technology.) A new heat-assisted design improves the desolvation efficiency and dramatically enhances the sensitivity for challenging molecules such as steroid hormones.

 

 

Superior robustness

The excellent robustness of the LCMS-8060NX can be seen most clearly during consecutive analyses of samples of biological origin that tend to contaminate instruments. We performed consecutive analyses of human blood plasma spiked with alprazolam on the LCMS-8060NX and plotted the resulting area values and area ratios (internal standard material: alprazolam-d5). To evaluate the robustness under even more demanding conditions, we performed a total of 15,000 consecutive analyses without using valves to remove impurities. As shown in the data below, the results were extremely stable, with an area value reproducibility of 1.79 %RSD and an area ratio reproducibility of 1.71 %RSD. This demonstrates the excellent stability of results with the LCMS-8060NX even during consecutive analyses of samples with large amounts of contaminants such as urine and blood plasma.

Results from Consecutive Analyses of Alprazolam-Spiked Human Blood Plasma