1. Reduces the time required for investigating conditions to 1/4
With the preparative work simulation function of LabSolutions analysis software and the Shim-pack Scepter LC column for analysis and preparative work, which offers excellent scalability*, the product reduces the time required for investigating preparative work conditions to approximately 1/4. The LH-40 Liquid Handler can be used as both a fraction collector and an autosampler for large-value injection with the liquid surface detection function (option). It also enables seamless purity checks through re-injection (option) of fractions after fractionation. Additional functions, including a sample rescue function to collect the sample from the system if an error occurs after an injection, a function to automatically extract the target peaks only, and high-purity preparative purification using detector signals for up to four channels, enable more efficient operations.
*A feature to acquire the same chromatogram (wave-shaped graph that indicates analysis results) from columns of all sizes
2. UFPLC high-purity purification system
Samples must be in a state of concentrated solution or dry powder to analyze their structure or store them. When a solution contains water, it takes time to dry and concentrate it. When salt such as trifluoroacetate has been added, it remains in the crystal of the compound, lowering the purity and negatively influencing pharmacokinetic studies and other testing. Shimadzu's unique high-purity purification system called UFPLC introduces solutions containing the target compound separated in a preparative column into a trap column. Furthermore, salt and water are removed from the fractionated solution by washing off salt and inducing elution with an organic solvent. This reduces the time required for drying to 1/16 of the conventional way, providing compounds with a high level of purity.
3. Flexible system scalability
Both the LH-40 and FRC-40 are designed to save installation space, requiring only half the space compared to other vendors' products. They support containers of a form and size suitable for the recovered quantity. Up to six units can be connected so up to 3240 10 mm diameter test tubes can be placed. Using the new Column Hub, up to six columns and four flow-line switching valves can be installed, enabling the compact configuration of various systems.